In the Hardy-Weinberg equation, what does 2pq represent?

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In the context of the Hardy-Weinberg equation, 2pq specifically represents the frequency of the heterozygous genotype in a population. This equation is a fundamental principle used in population genetics to describe the genetic variation within a population that is not evolving.

In the equation, p and q represent the frequencies of the dominant and recessive alleles, respectively. The term 2pq arises from the mathematical expansion of the binomial (p + q)^2, which results in the equations p^2 + 2pq + q^2. Here, p^2 represents the frequency of the homozygous dominant genotype, q^2 signifies the frequency of the homozygous recessive genotype, and 2pq accounts for the frequency of individuals that are heterozygous for the trait.

Thus, 2pq is crucial for understanding the genetic makeup of a population in equilibrium, highlighting how traits can be inherited and expressed across generations without changes in allele frequencies, assuming conditions are met.

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